Cell Cycle

Heatmap

heatmap

Acute myeloid leukemia patients clustered into 1 of 8 possible groups by their cell cycle proteins and phosphoprotein levels. Heatmap shows data from fresh bone marrow and peripheral blood samples.

 

 

 

 

 

 

 

 

 

 

Transition to Relapse

Principal Components

transition_relapse_fresh
Transitions between signaling network clusters for patients that relapsed. Notably, patients in cluster 5 and 6 either stayed in the same cluster or moved to cluster 4.

pca_fresh
Principal component analysis showing AML patient clusters from proteomics in relation to clusters of CD34+ normal bone marrow cells and relapsed patient samples.

Small Signaling Networks

Large Signaling Networks

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