Cell Cycle



Acute myeloid leukemia patients clustered into 1 of 8 possible groups by their cell cycle proteins and phosphoprotein levels. Heatmap shows data from fresh bone marrow and peripheral blood samples.











Transition to Relapse

Principal Components

Transitions between signaling network clusters for patients that relapsed. Notably, patients in cluster 5 and 6 either stayed in the same cluster or moved to cluster 4.

Principal component analysis showing AML patient clusters from proteomics in relation to clusters of CD34+ normal bone marrow cells and relapsed patient samples.

Small Signaling Networks

Large Signaling Networks

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